Link can use most weapons and items. He can use shields and has a spin attack that can hit multiple surrounding enemies at once!
Zelda can use most weapons and items. She uses Nayru's Love to protect herself from attacks and can use Din's Fire to attack faraway enemies.
Cadence can use most weapons and items. She can use shields and has a shovel attack that can stun nearby enemies.
Yves cannot use most weapons and active items. He can burrow into the ground to defend himself and has the ability to shoot projectiles from his snout.